Weakening HIV

Weakening HIV

One person’s fight against an HIV infection can decrease the virus’s ability to threaten its next victim, say Goepfert et al. (page 1009). Mutations that help the virus survive in one host decrease its ability to replicate in the next. HIV mutations that help the virus bypass the host’s immune system often fall within gag. This gene is a favorite target for mutations because, for some reason, G...

Evidence for HIV weakening over time.

Payne et al. (1) present evidence that HIV may be evolving into a less virulent form over time. Central to this evidence is a documented difference in the results from an in vitro assay measuring HIV replication capacity in the two populations studied (in Botswana and South Africa). Because there are significant cross-sectional correlations between the results of this assay and viral load and C...

Weakening Holonomy

and partly results of my Ph. D. student Richard Cleyton. It is a pleasure to thank the Erwin Schrrdinger Institute and the organisers of the program on Holonomy Groups in Diierential Geometry for their kind hospitality.

Weakening Holonomyandrew

Weakening Presburger Arithmetic

We consider logics on Z and N which are weaker than Presburger Arithmetic and we settle the following decision problem: given a k-ary relation on Z and N which is first order definable in Presburger Arithmetic, is it definable in these weaker logics? These logics, intuitively, are obtained in two different ways. First by introducing modulo and threshold counting predicates on the difference of ...